1 4 Dioxane Determination by GC Purge and Trap

1 4 Dioxane is a volatile organic compound found at residual levels as an impurity in many applications. This compound can be tested with purge and trap. It is a cleansing agent during the manufacturing of pharmaceuticals. It is also used in cosmetics, personal care products, household cleaners and employed as a stabilizer for chlorinated solvents, so it is commonly found at industrial sites contaminated with these solvents. Furthermore, its potential release into the environment can result in the contamination of groundwater. The Environmental Protection Agency (EPA) has classified it as a likely carcinogen. Thus it is essential to be able to detect it at low concentration levels. It has been identified as a potential carcinogen to humans. The International Agency for Research on Cancer (IARC) and the Department of Health and Human Services National Toxicology Program (NTP) recognize this.