1 4 Dioxane Determination by GC Purge and Trap
Abstract
1 4 Dioxane is a volatile organic compound found at residual levels as an impurity in many applications. It is a cleansing agent during the manufacturing of pharmaceuticals. It is also used in cosmetics, personal care products, household cleaners It is also used in cosmetics, personal care products, and household cleaners. And employed as a stabilizer for chlorinated solvents, so it is commonly found at industrial sites contaminated with these solvents. Furthermore, its potential release into the environment can result in the contamination of groundwater. The Environmental Protection Agency (EPA) has classified it as a likely carcinogen. Thus it is essential to be able to detect it at low concentration levels. It has been identified as a potential carcinogen to humans. The International Agency for Research on Cancer (IARC) and the Department of Health and Human Services National Toxicology Program (NTP) recognize this.
Introduction
1 4 Dioxane is completely miscible in water and does not readily biodegrade in the environment. Due to its miscibility in water, it has very poor purge efficiency and as a consequence, higher detection limits. In order to better detect 1 4 Dioxane, many laboratories use a heated purge cycle and/or purge larger volumes of samples. Furthermore, laboratories employ the Selective Ion Monitoring (SIM) mode of the Mass Spectrometer (MS) for better detection.
Further problems exist due to the sparge vessel even after rinsing. Thus, many labs run 1 4 Dioxane water samples in soil mode in order to avoid this problem. The EST Analytical Centurion WS has a patented water transfer mode that automates the water sample transfer to a separate vial for sample purging in the soil station while complying with USEPA Method 5030 requirements of keeping the sample vial closed before sample purging. This application will examine 1 4 Dioxane sampling and analysis using purge and trap concentration of water samples using the EST Analytical Evolution concentrator and the soil mode of the Centurion autosampler.
